The Charity was set up as a support organisation in 1986 to fund the first transplants in the North West and to assist in funding the development of a transplant centre for heart and lung transplantation. In 1995, it was formally recognised as a charity with The Charity Commissioners and a private company limited by guarantee not having a share capital was formed. There are 10 trustees from various backgrounds - medical staff, patients and business supporters

Local support groups in Horwich, North Wales and the Wirral, South Cheshire & North Staffordshire, and Liverpool have been formed to raise money locally and feed donations to the main charity.  Others are planned to cover areas such as Stockport and Ashton under Lyne, North East and North West Manchester, Blackburn, Accrington, Burnley,and Blackpool and Preston.

The main objectives of the charity are "...the relief of sickness and the preservation and protection of good health by the provision of financial assistance to the programme of heart and lung transplantation and future clinical developments in heart and lung surgery at Wythenshawe Hospital..."

Over the years the charity has raised funds in the order of £6.6 million to provide the following at Wythenshawe Hospital:-

--Funding the first 50 transplants

--Providing one third of the cost of building the transplant centre

--Building four bungalows for accommodation of transplant patients prior to returning home

--Building and equipping the Transplant Laboratory

--Funding the Laboratory for three years

--Funding a range of research projects

--Funding the salaries of three clinicians for three years

--Financing the building of £1.9 million Jim Quick Transplant Ward and six bedsits

--Providing new furniture and beds for the Jim Quick Ward